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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GOT1L1
All Species:
3.03
Human Site:
T337
Identified Species:
5.56
UniProt:
Q8NHS2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHS2
NP_689626.2
421
47305
T337
E
K
L
Q
L
L
G
T
P
G
S
W
G
H
I
Chimpanzee
Pan troglodytes
A5A6K8
413
46215
K325
E
E
W
T
G
N
V
K
T
M
A
D
R
I
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532809
406
45869
E316
E
W
K
Q
S
L
K
E
L
V
E
N
I
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q7TSV6
404
45439
G316
E
W
K
Q
S
L
K
G
V
V
E
N
M
M
L
Rat
Rattus norvegicus
P13221
413
46410
K325
K
E
W
K
G
N
V
K
T
M
A
D
R
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507985
380
42638
S297
K
I
V
R
V
T
W
S
N
P
P
S
Q
G
A
Chicken
Gallus gallus
P00504
412
45917
W319
S
P
Q
L
F
A
E
W
K
D
N
V
K
T
M
Frog
Xenopus laevis
NP_001080543
411
46052
W318
T
P
E
L
F
D
E
W
R
D
N
V
K
T
M
Zebra Danio
Brachydanio rerio
NP_998222
410
45964
D326
A
N
V
K
T
M
A
D
R
V
L
L
M
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_725534
437
48561
K354
M
R
T
A
L
R
D
K
L
V
A
L
G
T
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22067
408
45475
Q317
E
Q
W
N
Q
S
I
Q
A
M
S
S
R
I
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46645
405
44248
W312
S
S
D
M
Y
N
N
W
T
I
E
L
K
E
M
Baker's Yeast
Sacchar. cerevisiae
P23542
418
46039
S329
K
D
M
V
T
M
S
S
R
I
T
K
M
R
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.9
N.A.
76.7
N.A.
71.5
39.4
N.A.
33.9
37.7
37.7
39.6
N.A.
35.7
N.A.
35.3
N.A.
Protein Similarity:
100
57.9
N.A.
85.5
N.A.
81.7
57.7
N.A.
51.7
58.1
56.5
58.6
N.A.
52.4
N.A.
54.3
N.A.
P-Site Identity:
100
6.6
N.A.
20
N.A.
20
0
N.A.
0
0
0
0
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
26.6
N.A.
26.6
N.A.
26.6
33.3
N.A.
33.3
13.3
13.3
20
N.A.
26.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.8
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.5
46.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
8
8
0
8
0
24
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
8
8
8
0
16
0
16
0
0
0
% D
% Glu:
39
16
8
0
0
0
16
8
0
0
24
0
0
8
0
% E
% Phe:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
16
0
8
8
0
8
0
0
16
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% H
% Ile:
0
8
0
0
0
0
8
0
0
16
0
0
8
24
8
% I
% Lys:
24
8
16
16
0
0
16
24
8
0
0
8
24
0
8
% K
% Leu:
0
0
8
16
16
24
0
0
16
0
8
24
0
0
31
% L
% Met:
8
0
8
8
0
16
0
0
0
24
0
0
24
16
24
% M
% Asn:
0
8
0
8
0
24
8
0
8
0
16
16
0
0
0
% N
% Pro:
0
16
0
0
0
0
0
0
8
8
8
0
0
0
8
% P
% Gln:
0
8
8
24
8
0
0
8
0
0
0
0
8
0
0
% Q
% Arg:
0
8
0
8
0
8
0
0
24
0
0
0
24
16
0
% R
% Ser:
16
8
0
0
16
8
8
16
0
0
16
16
0
0
0
% S
% Thr:
8
0
8
8
16
8
0
8
24
0
8
0
0
24
0
% T
% Val:
0
0
16
8
8
0
16
0
8
31
0
16
0
0
0
% V
% Trp:
0
16
24
0
0
0
8
24
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _